Knowledge
In recent years, the application of ozone in the medical field has gradually attracted wide attention and become a new frontier of multidisciplinary approach. As a unique substance, ozone has shown great potential in many medical fields. The following will introduce the application of ozone in medicine from different aspects in detail.
First, the application of ozone in stomatology
The application of ozone in stomatology began in the 1980s, but its application in medicine can be traced back to the 1930s. The application of ozone in stomatology can effectively eliminate a variety of microorganisms. The strong oxidation of ozone makes it have a significant killing effect on bacteria, fungi and other pathogens in the mouth. For example, in the treatment of dental caries, periodontitis and other oral diseases, ozone can destroy the membrane of pathogens, interfere with their metabolic processes, and so on, to achieve the purpose of sterilization and inflammation.
Broad application background: Ozone has a broad application background in stomatology. It can be used for oral disinfection, dental caries treatment, periodontitis treatment and many other aspects. In terms of oral disinfection, ozone can quickly kill bacteria and viruses in the mouth, reducing the risk of infection. In the treatment of dental caries, ozone can soften caries bad tissue, easy to remove, but also can promote the remineralization of teeth, prevent the further development of dental caries. In the treatment of periodontitis, ozone can reduce inflammatory response and promote the repair of periodontal tissue.
Second, the application of ozone in multidisciplinary day surgery
Application Model and feasibility study: The application of oxygen-ozone therapy in multidisciplinary day surgery is becoming more and more widespread, and its data and professional scientific literature support it to attract more and more hospital attention. A feasibility study has been carried out, with a particular focus on the specialist section of the Hospital SAN Fermo Della Bataglia Sant Ana Como in Italy. The application model is proposed in this study, which provides a reference for the application of oxygen-ozone therapy in multidisciplinary day surgery.
Expanding the scope of treatment: The application of oxygen-ozone therapy can expand the scope of treatment in hospitals and provide more treatment options for patients. The application of this therapy in multidisciplinary day surgery can not only improve the treatment effect, but also shorten the hospital stay of patients and reduce medical costs.
The general application of ozone in medicine
Initial research and widespread use: The use of ozone became a common practice in Germany after initial research by Dr. H.h. Wolff (1979). Today, more than 12,000 doctors use ozone in Germany, but it was only after Bocci's research that ozone became very skilled in chronic inflammatory diseases or orthopedics. Ozone has a wide range of applications in medicine, including chronic inflammatory diseases, orthopedics and other fields.
Mechanism of action and effectiveness: Ozone has been shown to be very effective and absolutely non-toxic when used in appropriate doses, and it can work by inducing well-tolerated oxidative stress, whether in autologous blood therapy or in orthopedics. The action mechanism of ozone includes direct mechanism and indirect mechanism. The direct mechanism is mainly used for local treatment through free radical reaction; Indirect mechanisms play a role in systemic therapy, where "ozone peroxides" are directly reduced by the glutathione system, notifying nuclear factors to initiate regulation.
The application of ozone in chronic inflammatory diseases
Role of low dose ozone: Low dose ozone acts as a biological regulator in chronic inflammatory diseases. In these diseases, the biochemical characteristics are characterized by high oxidative stress and impaired regulation. In whole-body applications, "ozone peroxide" is able to replace H₂O₂ in its specific regulatory function, restore REDOX signals, and improve antioxidant capacity.
Take rheumatoid arthritis as an example: Rheumatoid arthritis, as a model of chronic inflammation, typically reflects the pharmacological effects of ozone in preclinical and clinical trials. Superoxide dismutase (SOD), catalase (CAT), and ultimately reduced glutathione (GSH) were increased, followed by a significant reduction in oxidative stress, down-regulation of inflammatory cytokines, and improvement in clinical status.
The application of ozone in musculoskeletal medicine
Treating multiple musculoskeletal disorders: Despite ongoing debate over toxicity and administration, ozone has shown promise in managing several musculoskeletal disorders, regulating pain and inflammation. Applications of ozone in musculoskeletal medicine include the treatment of fractures, osteoarthritis and chronic pain syndromes.
Existing problems and future research directions: The study also raises questions about potential toxicity, heterogeneity of patient responses, and the hazards of oxidants. More high-quality studies are needed in the future to refine the indication, efficacy, and safety of ozone in musculoskeletal medicine.
Application of ozone in veterinary medicine
Still emerging: The therapeutic use of ozone and its derivatives in veterinary medicine is still emerging. The chemical instability of gaseous ozone makes it necessary to prepare it on an AD hoc basis, and it is essential that the highest quality standards for ozone therapy are met in publications.
Challenges and future prospects: The large number of methods for administering ozone in different animal species, the predominance of case reports, the lack of consistent evaluation of results, and the inadequate standardization of treatment procedures are all issues facing its promotion and official approval. Further study of the mechanism of action of this biological oxidation therapy could open up new prospects for its application in veterinary medicine, and the key is to improve the understanding of the qualitative/quantitative characteristics of ozone and its derivatives.
Shaanxi Miaokang Medical Technology Co., Ltd had R&d and produce Ozone therapy device
is a comprehensive integrator engaged in medical instrument research and development, sales, medical technology research and promotion, and investment in medical institutions. The main research and development of medical ozone therapy equipment, extracorporeal shock wave therapy equipment and other products.
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In summary, the application of ozone in the medical field covers a variety of fields such as stomatology, multidisciplinary day surgery, general medicine, chronic inflammatory diseases, musculoskeletal medicine, and veterinary medicine, demonstrating a new frontier of multidisciplinary approaches. With the in-depth study of the mechanism of ozone and the continuous exploration of clinical application, the application prospect of ozone in the medical field will be more broad.
