Knowledge
Supplement-enhanced ozone therapy (Ozone therapy) is a promising therapeutic approach that has received a lot of attention in recent years. The following will describe in detail the role of supplements in enhancing ozone therapy and related research results.We use Ozone therapy machine to finish it.
First,Research background of supplement-enhanced ozone therapy
As a new treatment method, ozone therapy has shown certain potential in many fields. However, the use of ozone therapy alone may have certain limitations. To improve the effectiveness of ozone therapy, researchers began to explore the use of supplements to enhance the effects of ozone therapy. Supplements can work synergistically with ozone through different mechanisms, thereby improving the therapeutic effect.
Second, the role of different supplements in enhancing ozone therapy
(1) Zinc supplement combined with ozone therapy for diabetic foot ulcer
In a study of patients with diabetic foot ulcers, researchers used tropical ozone therapy and autologous blood therapy (blood ozone therapy), while giving the patients 50mg of zinc supplements daily. After two months of treatment, the patient's diabetic foot ulcer healed significantly, the inflammation was reduced, the wound closed, and there were no side effects. In addition, C-reactive protein levels in patients decreased significantly during treatment, indicating that the infection was effectively suppressed. This suggests that zinc supplementation combined with ozone therapy is an effective new way to treat diabetic foot ulcers.
(2) The effects of vitamin C and E supplements on ozone-sensitive subjects
A double-blind, cross-controlled study was conducted in 14 ozone-sensitive subjects to determine whether vitamin C (500mg/day) and E (100mg/day) supplementation reduced lung function, airway inflammation, and epithelial damage after ozone exposure (0.2ppm, 2 hours). However, the findings showed that despite increased plasma concentrations of vitamin C and vitamin E after supplementation, and increased airway concentrations of vitamin C after ozone exposure, vitamin supplements did not protect subjects from ozone-induced symptoms. After exposure to ozone, FEV1 decreased significantly, and the decrease was similar after vitamin supplementation and placebo treatment (-8.5% and -7.3%, respectively). Similarly, the magnitude of ozone-induced neutrophilism was similar after the two treatments.
Third, peppermint essential oil enhances the antibacterial effect of ozone
The researchers investigated the antibacterial potential of Mentha piperita essential oil (MpEO) for enhancing ozone against Gram-positive and Gram-negative bacteria and fungi. Peppermint essential oil was obtained by water distillation and analyzed by gas chromatography-mass spectrometry. Bacterial inhibition/bacterial mass growth was measured by broth microdilution method, and bacterial/mycelial growth rate (BGR/MGR) and bacterial/mycelial inhibition rate (BIR/MIR) were determined by spectrophotometric light density reading (OD). The results showed that after 55 seconds of single ozone exposure, the maximum effect on the following strains was: Staphylococcus aureus > Pseudomonas aeruginosa > Escherichia coli > Candida albicans > Streptococcus mutans. When 2% of peppermint essential oil (MIC) was added, these strains reached the maximum effect in 5 seconds, and the effect intensity was: Candida albicans > Escherichia coli > Pseudomonas aeruginosa > Staphylococcus aureus > Streptococcus mutans. The findings suggest that the combination of ozone with peppermint essential oil offers a new alternative therapy for the treatment of plaque biofilms and helps control oral disease-causing microorganisms.
Fourth, potassium ferrite enhanced ozone treatment of pharmaceutical wastewater
The catalytic ozonation effect of potassium ferrite reduction products on refractory organic compounds was verified by experiments with secondary effluent from a pharmaceutical wastewater treatment plant. The effect of potassium ferrite reduction products on ozone decomposition was studied by measuring the change of ozone concentration in water. Differences in ozone treatment with and without potassium-ferrite, and the role of potassium-ferrite reduction products in ozone-treated contaminants were investigated by analyzing measures of dissolved organic carbon (DOC), UV₂₅ Absorption, and fluorescent organics. The results show that:
The decomposition rate of ozone in aqueous solution containing potassium ferrite reduction products is higher than that in aqueous solution without potassium ferrite reduction products, indicating that potassium ferrite reduction products have catalytic capacity for ozone decomposition.
The combined treatment of ozone and potassium ferrite resulted in a 29.5% improvement in the removal rate of DOC and a 26% improvement in the removal rate of UV₂₅₄ compared to the ozone treatment alone.
The presence of the potassium ferrite reduction products improved the ozone treatment effect by 14.9% and 29.3%, respectively, compared to the residual DOC and UV₂₅₄ contents after treatment with potassium ferrite alone. These results show that the reduction products of potassium ferrite can promote the oxidation of refractory organic matter in secondary effluent by ozone, and the multistage oxidation system of potassium ferrite and ozone is technically feasible.
Fifth, low level phosphorus supplementation enhances the hydraulic performance and treatment efficiency of biological filtration
The John Kubala (JK) and Pierce-Burch (PB) water treatment facilities in Arlington, Texas, face complex problems with operations and water quality. While ozone/biological filtration systems have performed well over the years, they have occasionally experienced process issues, including reduced filtration run times, poor drainage, odors, and manganese breakthroughs. As part of the Water Research Foundation's customized collaborative project, the study focused on evaluating ways to restore and enhance the performance of existing full-scale ozone/biofiltration processes by supplementing with phosphorus. The results show that low level phosphorus supplementation can enhance the hydraulic performance and treatment efficiency of biofilters.
Sixth,the application of ozone therapy in hemodialysis patients and the potential role of supplements
The effect of ozone therapy on hemodialysis patients with serious complications was studied. Seventy-five hemodialysis patients were included in the study, of whom 60 had peripheral arterial occlusive disease and 23 had previously undergone unilateral lower limb amputation (group 1). Fifteen patients had significant joint pain due to α2-microglobulin deposition (group 2). All patients received analgesia. Following the protocol of the Italian Association for Oxygen-Ozone Therapy (SIOOT), the patient underwent high-dose ozone autohemotherapy, subcutaneous ozone infusion, and body exposure to oxygen/ozone mixtures via a bag. Questionnaires were given to patients at the beginning and end of ozone treatment to assess the effects of treatment. Ischemic ulcers heal completely in many patients. 88% of patients reported positive subjective results after ozone therapy. Patients in both groups 1 and 2 reported significantly reduced pain perception. Analgesic drug use was reduced in 78% of patients, and normal sleep/wake cycles were restored in 72% of patients. 67% of patients reported increased physical activity. This indicates that ozone therapy can improve the quality of life of hemodialysis patients, reduce bone pain and alleviate the clinical symptoms of peripheral vascular diseases. However, it is not clear whether there are specific supplements in hemodialysis patients that can further enhance the effects of ozone therapy.
Seventh, effects of percutaneous ozone therapy and supplements
The effects of percutaneous ozone exposure in a sauna were studied in 15 healthy volunteers. A large number of parameters were measured before exposure, at the end of exposure, and at 0.5, 1, and 24 hours after exposure. The control group (six volunteers) was exposed only to oxygen under the same experimental conditions as the ozone-treated group. Subjects exposed to ozone did not show significant intra-group and inter-group differences in weight change, blood pressure, and hematological parameters compared to controls, except for significant increases in plasma levels of interleukin-8, total antioxidant status (TAS), and thiobarbituric acid reactive substances (TBARS) at the end of treatment. However, all values returned to normal 24 hours after ozone treatment. This suggests that percutaneous ozone application may induce an acute and calculable form of oxidative stress similar to that observed after high-dose ozonation autohemotherapy. But it is unclear whether there are specific supplements that can enhance the effects of percutaneous ozone therapy.
Eighth,the effect of ozone therapy on fungi that cause gray nails and the need for potential supplements
The effects of different doses of ozone on the main fungi causing nail ash in vitro were studied. The dermatophytes Trichophyton rubra (ATCC 28,188) and Microspora gypsiformis (ATCC 24,102) were cultured at 28°C for 14 days. Treatment was divided into nine experimental groups according to the ozone dose applied: control group 0mg/m² : fungal culture but no treatment; The cultured fungi were treated with ozone at doses 157, 314, 471, 628, 785, 943, 1100 and 1257mg/m², respectively. The main results showed that local ozone therapy effectively reduced the germination rate of Trichophyton rubrum and Microspora gypsiformis during all experimental periods, achieving complete eradication at 628mg/m² and 1257mg/m², respectively. It is not known if there are specific supplements that can further enhance the therapeutic effect of ozone therapy on gray nails.
In summary, supplements have some potential in enhancing ozone therapy, but different supplements have different effects in different disease treatments. Future research is needed to further explore more effective supplements and the best way to combine them with ozone therapy to improve treatment effectiveness and lead to better treatment options for patients.
Shaanxi Miaokang Medical Technology Co., Ltd had R&d and produce Ozone therapy machine
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